The packaging of eukaryotic DNA into chromatin sterically occludes polymerases, recombinases and repair enzymes. How chromatin structure changes to allow their actions is unknown. We constructed ...
Studies using X-ray crystallography, NMR and cryo-electron microscopy (cryo-EM) reveal that linker histones (H1) bind to nucleosomes via electrostatic interactions and that this binding can occur in ...
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